Synthesis of New Oxazin Compounds Derived from Furfural, Chalcons and Schiff Bases

Volume 1 - Issue 3

Mohammad S Al Ajely¹* and A M Noori²

Received:June 04, 2019   Published:June 14, 2019

DOI: 10.32474/LOJPCR.2019.01.000113

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Abstract

Oxazine compounds have been succeeded to be used for versatile applications in various area of pharmacy, medicine and other biological uses such as Antiplatet aggregation activity, antidiabetic ,antidepressant activity ,In the investigation some new oxazine compounds have been synthesized using different routes [1]. The oxazine (A2-6) were prepared from the corresponding chalcone compounds (A1-6)by treatment of ethyl urea with these chalcones. oxazine (A5-8)were prepared from the cyclization of the corresponding compounds (A4-7) by formaldehyde compounds (A4-8 )themselves were prepared by reduction of Schiff bases (A3- 7) using NaBH4 .The third series of oxazines (A6-9)were synthesized by the reaction of furfural with hydroxyl Aromatic Compounds in methanolic ammonia. The synthesized compounds were studied by IR spectroscopy and are discussed [2].

Keywords: Oxazines; Furfural; Chalcones; Schiff bases

Abstract| Introduction| Expermintal| Results and Discussion| Conclusion| Acknowledgement| References|